Pulis is very much starting to gear up for Sunday's match and he insists there are no nerves.
"I don't really get nerves, no," he told us. "I think it is us looking forward to it."
It is the second season in succession that Stoke have reached the quarter-finals, last year going out to eventual winners Chelsea.
"The last major final was back in 1972 - it's great for the club and unbelievable opportunity - we got beat by Chelsea last year, and it is a great chance," he added.
As always happens in football, the fixture list always throws up a strange coincidence and it occurred last week when Stoke travelled to West Ham for a Premier League clash.
Things did not go according to plan as they were well beaten 3-0 and Pulis was not a happy man. He does, though, feel that his team will now be regarded as underdogs ahead of their weekend clash.
"After last weekend I think West Ham are favourites and we just have to do our best," he insisted.
The one thing in Stoke's favour is that the match is being played at The Britannia Stadium, Staffordshire's very own Coliseum.
Arguably, there is a not a harder place to head into in English football, and Pulis admits that the chance to play in front of their own fans is a glorious one.
"We have got the opportunity the chance to play at home which is always a major factor for us," he said.
"It is a game away from Wembley, the opportunity, for us, for the fans and that is something to look forward to."
The Stoke boss does not like to look ahead to Wembley too much and knows they have a huge task in-front of them.
"The big thing is the game this weekend, it will be fantastic for us, but the big thing is getting on the pitch on Sunday."